Department of Biomedical Engineering

GBE 407 | Course Introduction and Application Information

Course Name

Genomics and Proteomics

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
GBE 407	SPRING	2	2	3	6

Prerequisites	None
Course Language	English
Course Type	ELECTIVE_COURSE
Course Level	First Cycle
Mode of Delivery	Face to Face
Teaching Methods and Techniques of the Course	Discussion Group Work Q&A Lecture / Presentation
National Occupational Classification Code	-
Course Coordinator	Doç. Dr. Osman Doluca
Course Lecturer(s)	Doç. Dr. Osman Doluca
Assistant(s)	-

Course Objectives

The aim of this course is to introduce the methods which are used in protein biochemistry, bioinformatics and functional genomics In the scope of this lecture, responses of eukaryotic organisms to biotic and abiotic stress in all genome levels will be analyzed and the importance of personalized drug applications will be discussed.

Learning Outcomes

The students who succeeded in this course;

Name	Description	PC Sub	* Contribution Level
Name	Description	PC Sub	1	2	3	4	5
LO1	Identify genomic structures in various species.					X
LO2	Explain traditional and modern genomic techniques.					X
LO3	Apply comparative genomic applications.				X
LO4	Utilize proteomic approaches which are used in investigation of protein structure and function.					X
LO5	Discuss application areas of genomics and proteomics.					X

Course Description

Definition and application areas of genomics and proteomics approaches, structural genomics, functional genomics and usage of comparative genomic, analysis of genomes of livings, proteomic analyses. Recombinant DNA methods, genetically modified plants and animals and their use will be introduced.

Related Sustainable Development Goals

Course Category	Core Courses
	Major Area Courses	X
	Supportive Courses
	Media and Managment Skills Courses
	Transferable Skill Courses

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week	Subjects	Required Materials	Learning Outcome
1	Introduction to Genomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 1	17ef484c
2	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 1	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 2	17ef484c
3	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 2	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 3,4	17ef484c
4	DNA and Genome sequencing methods	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 5,7	431de204
5	Genome mapping	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 6	5e25ec2f
6	Genome assembly and annotation	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 8	431de204
7	Functional Genomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 9	5e25ec2f
8	Midterm I		-
9	Introduction to proteomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 10	fb1bb8a6
10	Two-dimensional Gel Electrophoresis	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 11	fb1bb8a6
11	Midterm II		-
12	Mass spectroscopy	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 12	fb1bb8a6
13	Protein identification by peptide mass fingerprinting	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 13	2006c59c
14	Protein sequencing techniques	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 14	2006c59c
15	Review of the course		-
16	Final exam		-

Course Notes/Textbooks	Concepts and Techniques in Genomics and Proteomics Nachimuthu Saraswathy- Ponnusamy Ramalingam- Elsevier- 2011. 978-1-907568-10-7
Suggested Readings/Materials	-

EVALUATION SYSTEM

Semester Activities	Number	Weighting	LO1	LO2	LO3	LO4	LO5
Quizzes / Studio Critiques	1	15	X	X
Homework / Assignments	1	15				X	X
Midterm	1	30	X	X	X	X
Final Exam	1	40		X	X	X	X
Total	4	100

ECTS / WORKLOAD TABLE

Semester Activities	Number	Duration (Hours)	Workload
Participation	-	-	-
Theoretical Course Hours	16	2	32
Laboratory / Application Hours	16	2	32
Study Hours Out of Class	14	2	28
Field Work	-	-	-
Quizzes / Studio Critiques	1	20	20
Portfolio	-	-	-
Homework / Assignments	1	24	24
Presentation / Jury	-	-	-
Project	-	-	-
Seminar / Workshop	-	-	-
Oral Exams	-	-	-
Midterms	1	22	22
Final Exam	1	22	22
		Total	180