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Department of Biomedical Engineering
GBE 310 | Course Introduction and Application Information
| Course Name |
Stem Cells
|
|
Code
|
Semester
|
Theory
(hour/week) |
Application/Lab
(hour/week) |
Local Credits
|
ECTS
|
|
GBE 310
|
SPRING
|
3
|
0
|
3
|
5
|
| Prerequisites | None | |||||
| Course Language | English | |||||
| Course Type | ELECTIVE_COURSE | |||||
| Course Level | First Cycle | |||||
| Mode of Delivery | Face-To-Face | |||||
| Teaching Methods and Techniques of the Course |
Discussion Group Work Q&A Lecture / Presentation |
|||||
| National Occupational Classification Code | - | |||||
| Course Coordinator |
|
|||||
| Course Lecturer(s) |
|
|||||
| Assistant(s) | - | |||||
| Course Objectives | The aim of this course is to learn the basics of stem cell biology, to gain information about the clinical applications of stem cells, and to discuss the role of stem cells in drug discovery. | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning Outcomes |
The students who succeeded in this course;
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||
| Course Description | Embryonic stem cells, Blood stem cells, Adult stem cells, Tissue engineering, Cell therapy, Drug discovery | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Related Sustainable Development Goals |
-
|
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|
|
Core Courses |
|
| Major Area Courses |
X
|
|
| Supportive Courses |
|
|
| Media and Managment Skills Courses |
|
|
| Transferable Skill Courses |
|
WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES
| Week | Subjects | Required Materials | Learning Outcome |
| 1 | Stem Cells, Properties, Types and Stem Cell Niche | Stem Cell Engineering: Principles and Applications | LO1 |
| 2 | Human Embryonic and Induced Multipotential Stem Cells | Stem Cell Engineering: Principles and Applications | LO1 |
| 3 | Genetic Modification of Human Embryonic and Induced Multipotential Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 7 | LO1 |
| 4 | Hematopoietic Stem Cells - Therapeutic Potential of Embryonic Stem Cell-Derived Blood Cells | Stem Cell Engineering: Principles and Applications Chapter 6 | LO2 |
| 5 | Mesenchymal Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 7 | LO2 |
| 6 | Potential of Selectively Cultured Adult Stem Cells Reinserted into Tissues | Stem Cell Engineering: Principles and Applications Chapter 4 | LO2 |
| 7 | Immune Barriers in Cell Therapy with Embryonic Origin Allogeneic Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 8 | LO2 |
| 8 | Midterm Exam | - | |
| 9 | Tissue Engineering | Stem Cell Engineering: Principles and Applications Chapter 12 | LO3 |
| 10 | Endothelial Progenitor Cells for Vascular Repair | Stem Cell Engineering: Principles and Applications Chapter 13 | LO3 |
| 11 | Biosynthetic Encapsulation Systems for Organ Engineering-A Look at Diabetes | Stem Cell Engineering: Principles and Applications Chapter 16 | LO3 |
| 12 | Adult Stem Cells in Drug Discovery | Stem Cell Engineering: Principles and Applications Chapter 21 | LO4 |
| 13 | Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing | Stem Cell Engineering: Principles and Applications Chapter 22 | LO4 |
| 14 | Article Presentations | - | |
| 15 | Semester Review | - | |
| 16 | Final Exam | - |
| Course Notes/Textbooks | Stem Cell Engineering: Principles and Applications. Editors Artmann & Minger and Hescheler. Springer (2011) |
| Suggested Readings/Materials |
Essentials of Stem Cell Biology – Robert Lanza & Anthony Atala - Elsevier Principles of Stem Cell Biology and Cancer – Future Applications and Therapeutic – Editors: Tarik Regad & Thomas J Sayers & Robert Rees – Wiley Blackwell Stem Cell Biology – Edited by Daniel R Marshak Richard L Gardner & David Gottlieb – Cold Spring Harbor Laboratory Press |
EVALUATION SYSTEM
| Semester Activities | Number | Weighting | LO1 | LO2 | LO3 | LO4 | LO5 |
| Quizzes / Studio Critiques | 1 | 5 | X | ||||
| Homework / Assignments | 1 | 5 | X | X | |||
| Presentation / Jury | 1 | 20 | X | X | |||
| Project | 1 | 15 | X | X | |||
| Midterm | 1 | 25 | X | X | X | ||
| Final Exam | 1 | 30 | X | X | X | X | X |
| Total | 6 | 100 |
ECTS / WORKLOAD TABLE
| Semester Activities | Number | Duration (Hours) | Workload |
|---|---|---|---|
| Participation | - | - | - |
| Theoretical Course Hours | 16 | 3 | 48 |
| Laboratory / Application Hours | - | - | - |
| Study Hours Out of Class | 12 | 1 | 12 |
| Field Work | - | - | - |
| Quizzes / Studio Critiques | 1 | 5 | 5 |
| Portfolio | - | - | - |
| Homework / Assignments | 1 | 5 | 5 |
| Presentation / Jury | 1 | 10 | 10 |
| Project | 1 | 20 | 20 |
| Seminar / Workshop | - | - | - |
| Oral Exams | - | - | - |
| Midterms | 1 | 20 | 20 |
| Final Exam | 1 | 30 | 30 |
| Total | 150 |
COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP
| # | PC Sub | Program Competencies/Outcomes | * Contribution Level | ||||
| 1 | 2 | 3 | 4 | 5 | |||
| No program competency data found. | |||||||
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest
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