| Course Name |
Stem Cells
|
|
Code
|
Semester
|
Theory
(hour/week) |
Application/Lab
(hour/week) |
Local Credits
|
ECTS
|
|
GBE 310
|
SPRING
|
3
|
0
|
3
|
5
|
| Prerequisites | None | |||||
| Course Language | English | |||||
| Course Type | ELECTIVE_COURSE | |||||
| Course Level | First Cycle | |||||
| Mode of Delivery | Face-To-Face | |||||
| Teaching Methods and Techniques of the Course |
Discussion Group Work Q&A Lecture / Presentation |
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| National Occupational Classification Code | - | |||||
| Course Coordinator |
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| Course Lecturer(s) |
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| Assistant(s) | - | |||||
| Course Objectives | The aim of this course is to learn the basics of stem cell biology, to gain information about the clinical applications of stem cells, and to discuss the role of stem cells in drug discovery. | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning Outcomes |
The students who succeeded in this course;
|
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| Course Description | Embryonic stem cells, Blood stem cells, Adult stem cells, Tissue engineering, Cell therapy, Drug discovery | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Related Sustainable Development Goals |
-
|
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|
|
Core Courses |
|
| Major Area Courses |
X
|
|
| Supportive Courses |
|
|
| Media and Managment Skills Courses |
|
|
| Transferable Skill Courses |
|
| Week | Subjects | Required Materials | Learning Outcome |
| 1 | Stem Cells, Properties, Types and Stem Cell Niche | Stem Cell Engineering: Principles and Applications | LO1 |
| 2 | Human Embryonic and Induced Multipotential Stem Cells | Stem Cell Engineering: Principles and Applications | LO1 |
| 3 | Genetic Modification of Human Embryonic and Induced Multipotential Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 7 | LO1 |
| 4 | Hematopoietic Stem Cells - Therapeutic Potential of Embryonic Stem Cell-Derived Blood Cells | Stem Cell Engineering: Principles and Applications Chapter 6 | LO2 |
| 5 | Mesenchymal Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 7 | LO2 |
| 6 | Potential of Selectively Cultured Adult Stem Cells Reinserted into Tissues | Stem Cell Engineering: Principles and Applications Chapter 4 | LO2 |
| 7 | Immune Barriers in Cell Therapy with Embryonic Origin Allogeneic Stem Cells | Stem Cell Engineering: Principles and Applications Chapter 8 | LO2 |
| 8 | Midterm Exam | - | |
| 9 | Tissue Engineering | Stem Cell Engineering: Principles and Applications Chapter 12 | LO3 |
| 10 | Endothelial Progenitor Cells for Vascular Repair | Stem Cell Engineering: Principles and Applications Chapter 13 | LO3 |
| 11 | Biosynthetic Encapsulation Systems for Organ Engineering-A Look at Diabetes | Stem Cell Engineering: Principles and Applications Chapter 16 | LO3 |
| 12 | Adult Stem Cells in Drug Discovery | Stem Cell Engineering: Principles and Applications Chapter 21 | LO4 |
| 13 | Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing | Stem Cell Engineering: Principles and Applications Chapter 22 | LO4 |
| 14 | Article Presentations | - | |
| 15 | Semester Review | - | |
| 16 | Final Exam | - |
| Course Notes/Textbooks | Stem Cell Engineering: Principles and Applications. Editors Artmann & Minger and Hescheler. Springer (2011) |
| Suggested Readings/Materials |
Essentials of Stem Cell Biology – Robert Lanza & Anthony Atala - Elsevier Principles of Stem Cell Biology and Cancer – Future Applications and Therapeutic – Editors: Tarik Regad & Thomas J Sayers & Robert Rees – Wiley Blackwell Stem Cell Biology – Edited by Daniel R Marshak Richard L Gardner & David Gottlieb – Cold Spring Harbor Laboratory Press |
| Semester Activities | Number | Weighting | LO1 | LO2 | LO3 | LO4 | LO5 |
| Quizzes / Studio Critiques | 1 | 5 | X | ||||
| Homework / Assignments | 1 | 5 | X | X | |||
| Presentation / Jury | 1 | 20 | X | X | |||
| Project | 1 | 15 | X | X | |||
| Midterm | 1 | 25 | X | X | X | ||
| Final Exam | 1 | 30 | X | X | X | X | X |
| Total | 6 | 100 |
| Semester Activities | Number | Duration (Hours) | Workload |
|---|---|---|---|
| Participation | - | - | - |
| Theoretical Course Hours | 16 | 3 | 48 |
| Laboratory / Application Hours | - | - | - |
| Study Hours Out of Class | 12 | 1 | 12 |
| Field Work | - | - | - |
| Quizzes / Studio Critiques | 1 | 5 | 5 |
| Portfolio | - | - | - |
| Homework / Assignments | 1 | 5 | 5 |
| Presentation / Jury | 1 | 10 | 10 |
| Project | 1 | 20 | 20 |
| Seminar / Workshop | - | - | - |
| Oral Exams | - | - | - |
| Midterms | 1 | 20 | 20 |
| Final Exam | 1 | 30 | 30 |
| Total | 150 |
| # | PC Sub | Program Competencies/Outcomes | * Contribution Level | ||||
| 1 | 2 | 3 | 4 | 5 | |||
| 1 |
Engineering Knowledge: Knowledge of mathematics, science, basic engineering, computation, and related engineering discipline-specific topics; the ability to apply this knowledge to solve complex engineering problems. |
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| 1 |
Mathematics |
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| 2 |
Science |
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| 3 |
Basic Engineering |
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| 4 |
Computation |
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| 5 |
Related engineering discipline-specific topics |
LO1 LO2 LO3 | |||||
| 6 |
The ability to apply this knowledge to solve complex engineering problems |
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| 2 |
Problem Analysis: Ability to identify, formulate and analyze complex engineering problems using basic knowledge of science, mathematics and engineering, and considering the UN Sustainable Development Goals relevant to the problem being addressed. |
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| 3 |
Engineering Design: The ability to devise creative solutions to complex engineering problems; the ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions. |
||||||
| 1 |
Ability to design creative solutions to complex engineering problems |
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| 2 |
Ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions |
LO4 LO5 | |||||
| 4 |
Use of Techniques and Tools: Ability to select and use appropriate techniques, resources, and modern engineering and computing tools, including estimation and modeling, for the analysis and solution of complex engineering problems, while recognizing their limitations. |
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| 5 |
Research and Investigation: Ability to use research methods to investigate complex engineering problems, including literature research, designing and conducting experiments, collecting data, and analyzing and interpreting results. |
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| 1 |
Literature research for the study of complex engineering problems |
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| 2 |
Designing experiments |
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| 3 |
Ability to use research methods, including conducting experiments, collecting data. analyzing and interpreting results |
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| 6 |
Global Impact of Engineering Practices: Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals; awareness of the legal implications of engineering solutions. |
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| 1 |
Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals |
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| 2 |
Awareness of the legal implications of engineering solutions |
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| 7 |
Ethical Behavior: Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility; awareness of being impartial, without discrimination, and being inclusive of diversity. |
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| 1 |
Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility ethical responsibility |
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| 2 |
Awareness of being impartial and inclusive of diversity, without discriminating on any subject |
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| 8 |
Individual and Teamwork: Ability to work effectively, individually and as a team member or leader on interdisciplinary and multidisciplinary teams (face-to-face, remote or hybrid). |
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| 1 |
Ability to work individually and within the discipline |
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| 2 |
Ability to work effectively as a team member or leader in multidisciplinary teams (face-to-face, remote or hybrid) |
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| 9 |
Verbal and Written Communication: Taking into account the various differences of the target audience (such as education, language, profession) on technical issues. |
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| 1 |
Ability to communicate verbally |
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| 2 |
Ability to communicate effectively in writing |
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| 10 |
Project Management: Knowledge of business practices such as project management and economic feasibility analysis; awareness of entrepreneurship and innovation. |
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| 1 |
Knowledge of business practices such as project management and economic feasibility analysis |
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| 2 |
Awareness of entrepreneurship and innovation |
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| 11 |
Lifelong Learning: Lifelong learning skills that include being able to learn independently and continuously, adapting to new and developing technologies, and thinking questioningly about technological changes. |
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*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest
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