Department of Biomedical Engineering

BME 312 | Course Introduction and Application Information

Course Name

Biomaterials

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
BME 312	SPRING	2	2	3	5

Prerequisites	None
Course Language	English
Course Type	Required (Core Course)
Course Level	First Cycle
Mode of Delivery	Face-To-Face
Teaching Methods and Techniques of the Course	-
National Occupational Classification Code	-
Course Coordinator	Dr. Öğr. Üyesi Gizem Ayna Duran
Course Lecturer(s)	Dr. Öğr. Üyesi Gizem Ayna Duran
Assistant(s)	Araş. Gör. Duygu Geçkin Araş. Gör. Sude Pehlivan Akbuğday

Course Objectives

The aim of this course is to introduce biomaterials and their properties, the fundamental principles of materials science and engineering, the evaluation of the biomedical use and applications of engineering materials, and the investigation of the properties of biological materials.

Learning Outcomes

The students who succeeded in this course;

Name	Description	PC Sub	* Contribution Level
Name	Description	PC Sub	1	2	3	4	5
LO1	Will be able to explain the types, structures, and properties (physical, chemical, and mechanical) of biomaterials and their applications		X
LO2	Will be able to explain the concepts of biocompatibility and biodegradation through the surface properties of biomaterials			X
LO3	Will be able to explain the in-vivo use of biomaterials from which medical devices or products designed for different medical purposes are manufactured.			X
LO4	wiil be able to discuss the acute immune responses resulting from the interaction of biomaterials with the body under in vivo conditions and the body's reactions to these responses.		X
LO5	Will be able to design biomaterials using instrumental methods in accordance with the characteristics of biomaterials				X
LO6	Will be able to design experiments that can perform the analyses of biomaterials				X

Course Description

The course covers the structure and properties of biomaterials, their application areas, processing, degradation, and biocompatibility.

Related Sustainable Development Goals

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Managment Skills Courses
	Transferable Skill Courses

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week	Subjects	Required Materials	Learning Outcome
1	Introduction to Biomaterials	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 1)	LO1
2	The Chemical and Physical Structure of Biomaterials	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 2,3)	LO1
3	Mechanical Properties of Biomaterials	J.S.Temenoff , A.G.Mikos , Biomaterials-The Intersection og Biology and Materials Science, First Edition (2008). (Ch. 4)	LO1
4	Biomaterial Processing	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 5)	LO1
5	Surface Properties of Biomaterials-I	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 6)	LO2
6	Surface Properties of Biomaterials-II	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 7)	LO2
7	Degradation of Biomaterials	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 8)	LO3
8	MidTerm Exam		-
9	Biomaterials and Biocompatibility	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 9)	LO3
10	Interaction of Cells and Proteins with Biomaterials	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 10,11)	LO3
11	Implantation of Biomaterials and Innate Immune Response	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 12,13)	LO4
12	Wound Healing and the Presence of Biomaterials	Temenoff, J. S., & Mikos, A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101 (Ch. 14)	LO4
13	Biomaterial Design	Lab instructions	LO5
14	Biomaterial Experiment Design		LO6
15	Review of the course		-
16	Final Exam		-

Course Notes/Textbooks	Temenoff J. S. & Mikos A. G. (2008). Biomaterials: the intersection of biology and materials science (Vol. 1). Upper Saddle River: Pearson/Prentice Hall. ISBN: 978-0130097101
Suggested Readings/Materials	-

EVALUATION SYSTEM

Semester Activities	Number	Weighting	LO1	LO2	LO3	LO4	LO5	LO6
Laboratory / Application	1	25	X	X			X	X
Presentation / Jury	1	10	X	X	X	X	X	X
Midterm	1	25	X	X	X
Final Exam	1	40	X	X	X	X
Total	4	100

ECTS / WORKLOAD TABLE

Semester Activities	Number	Duration (Hours)	Workload
Participation	-	-	-
Theoretical Course Hours	16	2	32
Laboratory / Application Hours	16	2	32
Study Hours Out of Class	14	2	28
Field Work	-	-	-
Quizzes / Studio Critiques	-	-	-
Portfolio	-	-	-
Homework / Assignments	-	-	-
Presentation / Jury	1	8	8
Project	-	-	-
Seminar / Workshop	-	-	-
Oral Exams	-	-	-
Midterms	1	20	20
Final Exam	1	30	30
		Total	150