Department of Biomedical Engineering

BME 307 | Course Introduction and Application Information

Course Name

Biosensors

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
BME 307	SPRING	3	0	3	5

Prerequisites	-
Course Language	English
Course Type	ELECTIVE_COURSE
Course Level	First Cycle
Mode of Delivery	Face-To-Face
Teaching Methods and Techniques of the Course	-
National Occupational Classification Code	-
Course Coordinator	Dr. Öğr. Üyesi Gülizar Çalışkan
Course Lecturer(s)	Dr. Öğr. Üyesi Gülizar Çalışkan
Assistant(s)	-

Course Objectives

The aim of this course is to study the recognition of biosensors used in modern medicine. First, enzyme, antibody and nucleic acid based biosensors will be introduced and then the potentiometric, amperometric and optometric fundamentals of biosensors will be discussed. Finally, the future of biosensor technologies will be discussed.

Learning Outcomes

The students who succeeded in this course;

Name	Description	PC Sub	* Contribution Level
Name	Description	PC Sub	1	2	3	4	5
LO1	will be able to define terms related to biosensors				X
LO2	will be able to explain the working principles of biosensors and the principles of electrochemical basic science				X
LO3	will be able to learn about biosensor types for the detection of different parameters			X
LO4	will be able to discuss the potentiometric, calorimetric, optical, etc. technologies used in biosensors			X
LO5	will be able to compare current and innovative biosensor technologies with traditional methods			X

Course Description

Bioelectronic devices and basic transducers. Determined Substances. Biosensor Regulators: Potentiometric (Glass, Liquid, Solid State Membrane, Gas Sensitive Membrane Electrodes), Amperometric. Optical, Fluorescent, Calorimetric, and Other Regulatory Systems. Enzyme Electrodes, Substrate Electrodes. Immunosensors, aptamer based sensors, New approaches in biosensors.

Related Sustainable Development Goals

Course Category	Core Courses
	Major Area Courses	X
	Supportive Courses
	Media and Managment Skills Courses
	Transferable Skill Courses

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week	Subjects	Required Materials	Learning Outcome
1	Introduction to biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 1	LO1
2	Classification of Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 1	LO2
3	Enzyme Based Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1Chapter 3	LO3
4	Antibody, Protein and Peptide Based Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1Chapter 6	LO3
5	Nucleic Acid Based Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 7	LO3
6	Immobilization of Biochemical Elements in Biosensors-I	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 5	LO3
7	Immobilization of Biochemical Elements in Biosensors-II	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 5	LO3
8	Mid Term Exam	Mid Term Exam	-
9	Electrochemical Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 13	LO4
10	Optical Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 18	LO4
11	Thermochemical Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 9	LO4
12	Other Types of Biosensors	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 19	LO5
13	Current Applications in Biosensors-I	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 20-23	LO5
14	Current Applications in Biosensors-II	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 20-23	LO5
15	Current Applications in Biosensors-III	Banica, F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1 Chapter 20-23	LO5
16	Final Exam	Final Exam	-

Course Notes/Textbooks	Banica F. G. (2012). Chemical sensors and biosensors: fundamentals and applications. John Wiley & Sons. ISBN 978-0-470-71066-1.
Suggested Readings/Materials	-

EVALUATION SYSTEM

Semester Activities	Number	Weighting	LO1	LO2	LO3	LO4	LO5
Homework / Assignments	1	10	X	X	X	X	X
Presentation / Jury	1	20	X	X	X	X	X
Midterm	1	30	X	X	X
Final Exam	1	40	X	X	X	X	X
Total	4	100

ECTS / WORKLOAD TABLE

Semester Activities	Number	Duration (Hours)	Workload
Participation	-	-	-
Theoretical Course Hours	16	3	48
Laboratory / Application Hours	-	-	-
Study Hours Out of Class	14	2	28
Field Work	-	-	-
Quizzes / Studio Critiques	-	-	-
Portfolio	-	-	-
Homework / Assignments	1	5	5
Presentation / Jury	1	10	10
Project	-	-	-
Seminar / Workshop	-	-	-
Oral Exams	-	-	-
Midterms	1	24	24
Final Exam	1	35	35
		Total	150