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      FACULTY OF ENGINEERING

      Department of Biomedical Engineering

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      GBE 370 | Course Introduction and Application Information

      Course Name
      Molecular Immunology
      Code
      Semester
      Theory
      (hour/week)
      Application/Lab
      (hour/week)
      Local Credits
      ECTS
      GBE 370
      Fall/Spring
      3
      0
      3
      6

      Prerequisites
      None
      Course Language
      English
      Course Type
      Elective
      Course Level
      First Cycle
      Mode of Delivery -
      Teaching Methods and Techniques of the Course Discussion
      Group Work
      Q&A
      Lecture / Presentation
      National Occupation Classification -
      Course Coordinator
      • Dr. Öğr. Üyesi Yağmur Kiraz
      Course Lecturer(s)
      • Dr. Öğr. Üyesi Yağmur Kiraz
      Assistant(s) -
      Course Objectives The objective of this course is to teach the cells and tissues that comprise the immune system and the differences between innate and adaptive immunity. Also, it aims to explain the selection, tolerance, memory mechanisms of immune system and relationships between immunity and diseases. This course, according to genetics and bioengineering based studies, will provide important background knowledge especially on the topics of immune system mechanisms and their effect on disease durations.\n
      Learning Outcomes
      #
      Content
      PC Sub
      * Contribution Level
      1
      2
      3
      4
      5
      1Classify cells, receptors and molecules that are part of the immune system,
      2Discuss the key features of innate and adaptive immunity,
      3Explain the concept of B cell development and function, antibody formation, structure and effector function together with T cell development and function, cytokines and their essential functions, and effects on the immune system
      4Describe the basic concepts of antigen presentation and structure and function of antigen-presenting molecules,
      5Explain tumor immunity, autoimmunity and immunity to viruses and how immunity relates to diseases, design a research project on immunotherapy;
      6Discuss immunology-related research articles.
      Course Description This course will include discussion of the properties of innate and adaptive immunity, the cells of the immune system. Additionally, students will learn about antibody structure and function, antigen recognition, lymphocyte activation, and immunity to microbes. Immunity that relates to diseases will also be covered including autoimmunity, transplantation, immunity to viruses and tumor immunology.
      Related Sustainable Development Goals

       



      Course Category

      Core Courses
      Major Area Courses
      Supportive Courses
      Media and Management Skills Courses
      Transferable Skill Courses

       

      WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

      Week Subjects Related Preparation Learning Outcome
      1 Introduction to Immune System, Cells of the Immune System & Lymphoid Organs Janeway’s Immunobiology 9th Edition, Part I
      2 Innate Immunity Janeway’s Immunobiology 9th Edition, Part I
      3 Adaptive Immunity Janeway’s Immunobiology 9th Edition, Part IV
      4 B-Cells and Antibodies / Antibody Classes & Functions Janeway’s Immunobiology 9th Edition, Part II
      5 Antigen Presentation / MHC Classes Janeway’s Immunobiology 9th Edition, Part II
      6 T-Cell Activation and Signaling Janeway’s Immunobiology 9th Edition, Part IV
      7 T-Cell Receptors, Response Janeway’s Immunobiology 9th Edition, Part IV
      8 Midterm
      9 Autoimmunity Janeway’s Immunobiology 9th Edition, Part V
      10 Tumor Immunology / Immunotherapy Janeway’s Immunobiology 9th Edition, Part V
      11 Transplantation Janeway’s Immunobiology 9th Edition, Part V
      12 Immunity to Viruses / Vaccinology Janeway’s Immunobiology 9th Edition, Part V
      13 Research Paper Presentations TBD
      14 Research Paper Presentations TBD
      15 Review
      16 Final Exam

       

      Course Notes/Textbooks

      Janeway’s Immunobiology 9th Edition, Kenneth Murphy & Casey Weaver 2016, Garland Science
      ISBN-13: 9781315533247 ISBN: 1315533243

      Suggested Readings/Materials

      Kuby Immunology by Kindt, Goldsby and Osborne, 2007, W.H. Freeman and Company, New York, NY

      Primary journals:
      Vaccine, 
      Immunology, 
      Journal of Immunology, 
      Infection and Immunity, 
      Nature Reviews Immunology,
      Frontiers in Immunology.

       

      EVALUATION SYSTEM

      Semester Activities Number Weigthing LO 1 LO 2 LO 3 LO 4 LO 5 LO 6
      Participation
      Laboratory / Application
      Field Work
      Quizzes / Studio Critiques
      2
      15
      XXXX
      Portfolio
      Homework / Assignments
      Presentation / Jury
      1
      20
      XX
      Project
      1
      15
      XX
      Seminar / Workshop
      Oral Exams
      Midterm
      1
      20
      XXXX
      Final Exam
      1
      30
      XXXXXX
      Total
      333333

      Weighting of Semester Activities on the Final Grade
      6
      70
      Weighting of End-of-Semester Activities on the Final Grade
      1
      30
      Total

      ECTS / WORKLOAD TABLE

      Semester Activities Number Duration (Hours) Workload
      Theoretical Course Hours
      (Including exam week: 16 x total hours)
      16
      3
      48
      Laboratory / Application Hours
      (Including exam week: '.16.' x total hours)
      16
      0
      Study Hours Out of Class
      14
      2
      28
      Field Work
      0
      Quizzes / Studio Critiques
      2
      10
      20
      Portfolio
      0
      Homework / Assignments
      -
      0
      Presentation / Jury
      1
      20
      20
      Project
      1
      20
      20
      Seminar / Workshop
      0
      Oral Exam
      0
      Midterms
      1
      20
      20
      Final Exam
      1
      24
      24
          Total
      180

       

      COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

      #
      PC Sub Program Competencies/Outcomes
      * Contribution Level
      1
      2
      3
      4
      5
      1

      To have adequate knowledge in Mathematics, Science and Biomedical Engineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

      -
      -
      -
      -
      -
      2

      To be able to identify, define, formulate, and solve complex Biomedical Engineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

      -
      -
      -
      -
      -
      3

      To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

      -
      -
      -
      -
      -
      4

      To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Biomedical Engineering applications.

      -
      -
      -
      -
      -
      5

      To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Biomedical Engineering research topics.

      -
      -
      -
      -
      -
      6

      To be able to work efficiently in Biomedical Engineering disciplinary and multi-disciplinary teams; to be able to work individually.

      -
      -
      -
      -
      -
      7

      To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

      -
      -
      -
      -
      -
      8

      To have knowledge about global and social impact of Biomedical Engineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of engineering solutions.

      -
      -
      -
      -
      -
      9

      To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in engineering applications.

      -
      -
      -
      -
      -
      10

      To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

      -
      -
      -
      -
      -
      11

      To be able to collect data in the area of Biomedical Engineering, and to be able to communicate with colleagues in a foreign language.

      -
      -
      -
      -
      -
      12

      To be able to speak a second foreign language at a medium level of fluency efficiently.

      -
      -
      -
      -
      -
      13

      To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Biomedical Engineering.

      -
      -
      -
      -
      -

      *1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest


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