FACULTY OF ENGINEERING
Department of Biomedical Engineering
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BME 431 | Course Introduction and Application Information
| Course Name |
Micro-Electro-Mechanical Systems in Biomedical Applications
|
|
Code
|
Semester
|
Theory
(hour/week) |
Application/Lab
(hour/week) |
Local Credits
|
ECTS
|
|
BME 431
|
Fall/Spring
|
2
|
2
|
3
|
6
|
| Prerequisites |
None
|
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| Course Language |
English
|
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| Course Type |
Elective
|
|||||
| Course Level |
First Cycle
|
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| Mode of Delivery | - | |||||
| Teaching Methods and Techniques of the Course | - | |||||
| Course Coordinator | ||||||
| Course Lecturer(s) | ||||||
| Assistant(s) | - | |||||
| Course Objectives | This course aims to introduce Micro-Electro-Mechanical Systems (MEMS), give a background on micro-electrical, -mechanical, and -optical sensors, and their applications in Biomedical device and system design. |
| Learning Outcomes |
The students who succeeded in this course;
|
| Course Description | The course covers basic definitions and principles, design characteristics, manufacturing technologies for microfluidic and micro-total-analytic-system (µTAS) structures, micro electrical, micro mechanical and micro optical sensors, MEMS, bioMEMS and their applications for biomedical purposes including Lab-on-a-Chip analysis, implantable sensors and drug delivery. |
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Core Courses | |
| Major Area Courses |
X
|
|
| Supportive Courses | ||
| Media and Management Skills Courses | ||
| Transferable Skill Courses |
WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES
| Week | Subjects | Related Preparation |
| 1 | Fundamentals of MEMS for biomedical applications | Albert Folch. Introduction to BioMEMS, ISBN 9780367864965 (Ch.1) Shekhar Bhansali, Abhay Vasudev. MEMS for biomedical applications, ISBN-13: 978-0857091291 (Ch. 1) |
| 2 | Microfluidics: Fundamentals and Engineering Concepts | Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, ISBN: 978-0-387-28597-9 (Ch.1) |
| 3 | Molecular sensors and scale effect | John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, ISBN: 978-1-4557-7631-3 (Ch.1,2) |
| 4 | Micropatterning in MEMS | Albert Folch. Introduction to BioMEMS, ISBN: 978-1439818398 (Ch.2) |
| 5 | Electrical Transducers | John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, ISBN: 978-1-4557-7631-3 (Ch.4) Shekhar Bhansali, Abhay Vasudev. MEMS for biomedical applications, ISBN-13: 978-0857091291 (Ch. 2,4) |
| 6 | Optical Transducers | John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, ISBN: 978-1-4557-7631-3 (Ch.5) |
| 7 | Mechanical Transducers | John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineeringi, ISBN: 978-1-4557-7631-3 (Ch. 6) |
| 8 | Micropumps, Micromixers and Magnetic Particles | Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, ISBN: 978-0-387-28597-9 (Ch.2-6) |
| 9 | Review and Midterm Exam | |
| 10 | Nucleic Acid Amplification in Microsystems | Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, ISBN: 978-0-387-28597-9 (Ch.13) |
| 11 | Electrophoresis and Chromatography in Microstructures | Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, ISBN: 978-0-387-28597-9 (Ch.10,11) |
| 12 | Cytometry on Microfluidic Chips | Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, ISBN: 978-0-387-28597-9 (Ch.14) |
| 13 | MEMS for tissue engineering | Shekhar Bhansali, Abhay Vasudev. MEMS for biomedical applications, ISBN-13: 978-0857091291 (Ch. 7,8) Albert Folch. Introduction to BioMEMS, ISBN: 978-1439818398 (Ch.7) |
| 14 | Implantable microdevices | John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering , ISBN: 978-1-4557-7631-3 (Ch.7) Albert Folch. Introduction to BioMEMS, ISBN: 978-1439818398 (Ch.13,14) |
| 15 | Review of the course | |
| 16 | Final Exam |
| Course Notes/Textbooks | Albert Folch. Introduction to BioMEMS, Taylor & Francis Group (2013) ISBN: 978-1439818398
Shekhar Bhansali, Abhay Vasudev. MEMS for biomedical applications, Woodhead Publishing Limited (2012) ISBN: 978-0-85709-129-1
Steffen Hardt, Friedhelm Schönfeld. Microfluidic Technologies for Miniaturized Analysis Systems, Springer (2007) ISBN: 978-0-387-28597-9
John X. J. Zhang, Kazunori Hoshino. Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, Elsevier (2014) ISBN: 978-1-4557-7631-3 |
| Suggested Readings/Materials |
EVALUATION SYSTEM
| Semester Activities | Number | Weigthing |
| Participation | ||
| Laboratory / Application |
1
|
20
|
| Field Work | ||
| Quizzes / Studio Critiques | ||
| Portfolio | ||
| Homework / Assignments | ||
| Presentation / Jury | ||
| Project |
1
|
30
|
| Seminar / Workshop | ||
| Oral Exams | ||
| Midterm |
1
|
20
|
| Final Exam |
1
|
30
|
| Total |
| Weighting of Semester Activities on the Final Grade |
3
|
70
|
| Weighting of End-of-Semester Activities on the Final Grade |
1
|
30
|
| Total |
ECTS / WORKLOAD TABLE
| Semester Activities | Number | Duration (Hours) | Workload |
|---|---|---|---|
| Theoretical Course Hours (Including exam week: 16 x total hours) |
16
|
2
|
32
|
| Laboratory / Application Hours (Including exam week: '.16.' x total hours) |
16
|
2
|
32
|
| Study Hours Out of Class |
14
|
2
|
28
|
| Field Work |
0
|
||
| Quizzes / Studio Critiques |
0
|
||
| Portfolio |
0
|
||
| Homework / Assignments |
4
|
0
|
|
| Presentation / Jury |
0
|
||
| Project |
1
|
40
|
40
|
| Seminar / Workshop |
0
|
||
| Oral Exam |
0
|
||
| Midterms |
1
|
25
|
25
|
| Final Exam |
1
|
23
|
23
|
| Total |
180
|
COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP
|
#
|
Program Competencies/Outcomes |
* Contribution Level
|
||||
|
1
|
2
|
3
|
4
|
5
|
||
| 1 | To have adequate knowledge in Mathematics, Science and Biomedical Engineering; to be able to use theoretical and applied information in these areas on complex engineering problems. |
X | ||||
| 2 | To be able to identify, define, formulate, and solve complex Biomedical Engineering problems; to be able to select and apply proper analysis and modeling methods for this purpose. |
X | ||||
| 3 | To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose. |
X | ||||
| 4 | To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Biomedical Engineering applications. |
X | ||||
| 5 | To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Biomedical Engineering research topics. |
|||||
| 6 | To be able to work efficiently in Biomedical Engineering disciplinary and multi-disciplinary teams; to be able to work individually. |
X | ||||
| 7 | To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions. |
|||||
| 8 | To have knowledge about global and social impact of Biomedical Engineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of engineering solutions. |
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| 9 | To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in engineering applications. |
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| 10 | To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development. |
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| 11 | To be able to collect data in the area of Biomedical Engineering, and to be able to communicate with colleagues in a foreign language. |
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| 12 | To be able to speak a second foreign language at a medium level of fluency efficiently. |
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| 13 | To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Biomedical Engineering. |
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*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest
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