BME 407 | Course Introduction and Application Information

Course Name
Artificial Organs and Life Support Systems
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
BME 407
Fall/Spring
3
0
3
5

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Course Coordinator
Course Lecturer(s) -
Assistant(s) -
Course Objectives The objective of this course is to familiarize students with tissue engineering and artificial organs. The course covers basic techniques of of molecular biology, forces applied on the cells, the behavior of the cells. The course will continue with an introduction to the tissue engineering and the methods used in tissue engineering. Finally, the students will be introduced to artificial organs, their development and applications before finalizing with ethics of the use of artificial organs in medicine.
Learning Outcomes The students who succeeded in this course;
  • define the basic terminology related to tissue engineering and genetic engineering,
  • explain fundamental principles of mass transport and hydrodynamics,
  • discuss the cellular behavior, migration and adhesion,
  • recognize various biomaterials used in development of artificial organs,
  • define the working principles of artificial organs,
  • explain the basic principles of biomimetics,
  • discuss the methods used in tissue engineering.
Course Content Introduction to artificial organs, basic principles of mass transfer and fluidics, chemical reactions in biological system, recombinant DNA technology, biomaterials, basic principles of design of artificial organs (biomimetics), applications of artificial organs.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Basic Principles of Molecular Biology Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 1
2 Recombinant DNA Technology Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 3
3 Mass Transport and Hydrodynamics Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 7
4 Fundamentals of Stem Cell Tissue Engineering Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 30
5 Growth Factors Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 31
6 Extracellular Matrix Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 32
7 Cell Migration and Adhesion Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 33
8 Ara sınav / Midterm
9 Biomimetic Materials Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 39
10 Tissue Engineering Applications Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 50
11 Artificial Heart, Blood and Circulatory Assist Devices Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 63
12 Artificial Lungs and Blood Exchange Devices Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 66
13 Artificial Kidney and Pancreas Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 67, 71
14 Ethics of Tissue Engineering and Artificial Organs Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Chapter 76, 77
15 Review
16 Review of the Semester  

 

Course Textbooks Joseph D. Bronzino (Editor), Tissue Engineering and Artificial Organs (The Biomedical Engineering Handbook), CRC; 3rd edition (May 1, 2006). Course slides
References Larry L. Hench (Editor), Julian R. Jones (Editor), Biomaterials, artificial organs and tissue engineering (PBK), CRC, 2005

 

EVALUATION SYSTEM

Semester Requirements Number Percentage
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
2
10
Homework / Assignments
5
10
Presentation / Jury
1
10
Project
1
25
Seminar / Workshop
Portfolios
Midterms / Oral Exams
1
20
Final / Oral Exam
1
25
Total

Contribution of Semester Work to Final Grade
75
Contribution of Final Work to Final Grade
25
Total

ECTS / WORKLOAD TABLE

Activities Number Duration (Hours) Workload
Course Hours
Including exam week: 16 x total hours
16
3
48
Laboratory / Application Hours
Including exam week: 16 x total hours
16
Study Hours Out of Class
16
2
Field Work
Quizzes / Studio Critiques
2
4
Homework / Assignments
5
2
Presentation / Jury
1
7
Project
1
20
Seminar / Workshop
Portfolios
Midterms / Oral Exams
1
10
Final / Oral Exam
1
15
    Total
150

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Qualifications / Outcomes
* Level of Contribution
1
2
3
4
5
1

To have sufficient background in Mathematics, Basic sciences and Biomedical Engineering areas and the skill to use this theoretical and practical background in the problems of the Biomedical Engineering.

X
2

To identify, formulate and solve Biomedical Engineering-related problems by using state-of-the-art methods, techniques and equipment; to select and apply appropriate analysis and modeling methods for this purpose.

X
3

To analyze a complex system, system components or process, and to design with realistic limitations to meet the requirements using modern design techniques; to apply modern design techniques for this purpose.

X
4

To choose and use the required modern techniques and tools for analysis and solution of complex problems in Biomedical Engineering applications; to skillfully use information technologies.

X
5

To design and do simulation and/or experiment, collect and analyze data and interpret results for studying complex engineering problems or research topics of the discipline. 

X
6

To efficiently participate in intradisciplinary and multidisciplinary teams; to work independently.

X
7

To communicate both in oral and written form in Turkish; to have knowledge of at least one foreign language; to have the skill to write and understand reports, prepare design and production reports, present, give and receive clear instructions.

X
8

To recognize the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.

X
9

To behave ethically, to be aware of professional and ethical responsibilities; to have knowledge about the standards in Biomedical Engineering applications.

10

To have information about business life practices such as project management, risk management, and change management; awareness of entrepreneurship, innovation, and sustainable development.

X
11

To have knowledge about contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; awareness of the legal consequences of Biomedical Engineering solutions.

X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest