FACULTY OF ENGINEERING

Department of Biomedical Engineering

BME 401 | Course Introduction and Application Information

Course Name
Medical İmaging
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
BME 401
Fall/Spring
3
0
3
6

Prerequisites
None
Course Language
English
Course Type
Service Course
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course -
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives The aim of this course to introduce the students with the principles and technical aspects of medical imaging instrumentation, the physical principles of medical image data acquisition, and properties and presentation of medical images, and an overview of the computational and mathematical methods in medical image processing.
Learning Outcomes The students who succeeded in this course;
  • Define the principles and main technical aspects of medical imaging instrumentation and data acquisition
  • Identify major processes involved in formation of medical images
  • Recognize the imaging modality from their visualizations
  • Analyze efficacy and drawbacks of several medical imaging technologies
  • Define the principles and technical aspects of, and the need for basic image processing techniques.
  • Describe fundamental methods for enhancement, segmentation, and registration of medical images.
Course Description Principles of major medical imaging technologies including x-ray radiography, x-ray computed tomography (CT), ultrasonography, magnetic resonance imaging (MRI), and nuclear imaging (PET and SPECT). A brief discussion on the other emerging imaging technologies such as microscopic imaging. Storage, visualization, and processing of medical image data.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction and Overview: Introduction to medical imaging technology, systems, and modalities. Brief history; importance; applications; trends; challenges. Lecture notes
2 X-Ray: X-Ray physics; X-Ray generation, attenuation, scattering; dose Chapter 2; " Radiography", Paul Suetens, Second Edition, Cambridge University Press
3 CT Imaging: Basic principles of CT; reconstruction methods; artifacts; CT hardware Chapter 3; "X-ray Computed Tomography, Paul Suetens, Second Edition, Cambridge University Press
4 Medical Image Processing, Enhancement, Filtering: Basic image processing methods; Thresholding; Contrast enhancement; SNR characteristics; Filtering; Histogram modeling Chapter 1; "Introduction to Digital Image Processing", Paul Suetens, Second Edition, Cambridge University Press
5 Magnetic Resonance Imaging (MRI) - I: Mathematics of MR; spin physics; NMR spectroscopy; imaging principles and hardware; image artifacts Chapter 4; "Magnetic Resonance Imaging", Paul Suetens, Second Edition, Cambridge University Press
6 Magnetic Resonance Imaging (MRI) - II: Mathematics of MR; spin physics; NMR spectroscopy; imaging principles and hardware; image artifacts Chapter 4; "Magnetic Resonance Imaging", Paul Suetens, Second Edition, Cambridge University Press
7 Ultrasound Imaging: Ultrasound imaging and its applications. Chapter 6; "Ultrasound Imaging", Paul Suetens, Second Edition, Cambridge University Press
8 Review and Midterm
9 Medical Image Storage, Archiving and Communication Systems and Formats: Picture archiving and communication system (PACS); Formats: DICOM; Radiology Information Systems (RIS) and Hospital Information Systems (HIS) Lecture notes
10 Medical Image Visualization: Fundamentals of visualization; Surface and volume rendering/visualization; Animation; Interaction Chapter 8; "Visualization for Diagnosis and Therapy", Paul Suetens, Second Edition, Cambridge University Press
11 Nuclear Imaging: PET and SPECT Imaging methods; mathematical principles; resolution; noise effect; 3D imaging; positron emission tomography; single photon emission tomography Chapter 5; "Nuclear Medicine Imaging", Paul Suetens, Second Edition, Cambridge University Press
12 Medical Image Segmentation: Histogram-based methods; Region growing and watersheds; active contours; model-based segmentation; atlas-guided approaches Chapter 7; " Medical Image Analysis", Paul Suetens, Second Edition, Cambridge University Press
13 Medical Image Registration: Intensity-based methods; Cost functions; Optimization techniques Lecture notes
14 Emerging Technologies of Medical Imaging: Confocal, multi-photon microscopic imaging; Deconvolution microscopy Lecture notes
15 Presentation and Evaluation of Term Projects
16 Final

 

Course Notes/Textbooks Paul Suetens, "Fundamentals of Medical Imaging", Second Edition, Cambridge University Press, ISBN: 0521519152, 2009. Lecture Notes
Suggested Readings/Materials The Essential Physics of Medical Imaging , 2nd Edition, (2002) by J. T. Bushberg, J. A. Seibert, E. M. Leidholdt, J. M. Boone, Lippencott Williams & Wilkins Pulb. (Kluwer). Lecture slides will be distributed as softcopy.

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
4
20
Portfolio
Homework / Assignments
Presentation / Jury
Project
Seminar / Workshop
Oral Exams
Midterm
1
40
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
14
4
56
Field Work
0
Quizzes / Studio Critiques
4
0
Portfolio
0
Homework / Assignments
0
Presentation / Jury
0
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
1
38
38
Final Exam
1
38
38
    Total
180

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Biomedical Engineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

X
2

To be able to identify, define, formulate, and solve complex Biomedical Engineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

X
3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

X
4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Biomedical Engineering applications.

X
5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Biomedical Engineering research topics.

X
6

To be able to work efficiently in Biomedical Engineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Biomedical Engineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of engineering solutions.

X
9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in engineering applications.

X
10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

X
11

To be able to collect data in the area of Biomedical Engineering, and to be able to communicate with colleagues in a foreign language.

X
12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Biomedical Engineering.

X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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