FACULTY OF ENGINEERING

Department of Biomedical Engineering

BME 307 | Course Introduction and Application Information

Course Name
Biosensors
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
BME 307
Fall/Spring
3
0
3
5

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course -
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives The objective of this course to introduce biosensors used modern medicine. Initially the course will focus on biosensors using enzymatic reactions and affinity based recognition by nucleic acids and antibodies. In the following, potentiometric, amperometric and optical fundamentals of biosensors before discussing the future of biosensor technologies.
Learning Outcomes The students who succeeded in this course;
  • define terminology related to biosensors
  • explain electrochemical fundamentals
  • explain working principles of biosensors
  • choose appropriate biosensors for various biomarker parameters
  • solve problems related to development of novel biosensors
  • discuss the basics of potentiometric, calorimetric and optical technologies used in biosensors
  • discuss the innovations and trending technologies in the field of biosensors
Course Description The course covers Bioelectronic devices, Potentiometric, amperometric, Optical, Fluorescent, colorimetric and other biosensor systems, Enzyme electrodes, substrate electrodes, immunosensors, aptamer sensors, new approaches in biosensors.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction to Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 1
2 Classification of Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1,, Chapter 1
3 Enzymes Based Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 3
4 Antibody, Protein and Peptides Based Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 6
5 Nucleic Acid Based Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 7
6 Immobilization of Biochemical Elements of Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 5
7 MIDTERM
8 Electrochemical Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 13
9 Optical Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 18
10 Thermo chemical Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 9
11 Other Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 19
12 Current Application of Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 20-23
13 Current Application of Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 20-23
14 Current Application of Biosensors F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1, Chapter 20-23
15 Review
16 Final Exam

 

Course Notes/Textbooks

F.‐G. Bănică, Chemical Sensors and Biosensors: Fundamentals and Applications, Wiley, 2012, ISBN 978-0-470-71066-1.

Pier Andrea Serra (editor), Biosensors – Emerging Materials and Applications, 2011, ISBN 978-953-307-328-6.

Suggested Readings/Materials Jeong-Yeol Yoon, Introduction to Biosensors - From Electric Circuits to Immunosensors, Springer, 2013, ISBN 978-1-4419-6022-1 Pier Andrea Serra (Editor), Biosensors, 2010, ISBN 978-953-7619-99-2

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
10
Presentation / Jury
1
20
Project
Seminar / Workshop
Oral Exams
Midterm
1
30
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
55
Weighting of End-of-Semester Activities on the Final Grade
1
45
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
16
2
32
Field Work
0
Quizzes / Studio Critiques
0
Portfolio
0
Homework / Assignments
1
5
5
Presentation / Jury
1
20
20
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
1
20
20
Final Exam
1
25
25
    Total
150

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Biomedical Engineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

X
2

To be able to identify, define, formulate, and solve complex Biomedical Engineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

X
3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

X
4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Biomedical Engineering applications.

X
5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Biomedical Engineering research topics.

X
6

To be able to work efficiently in Biomedical Engineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Biomedical Engineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of engineering solutions.

X
9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in engineering applications.

10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Biomedical Engineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Biomedical Engineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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